• Bicalutamide contains a medicine called bicalutamide.
  • Bicalutamide is available in the branded form called Casodex.
  • This belongs to a group of medicines called ‘anti-androgens’.
  • bicalutamide is used to treat prostate cancer.

Why have I been prescribed Bicalutamide?

  • Bicalutamide contains a medicine called bicalutamide. This belongs to a group of medicines called ‘anti-androgens’. Bicalutamide is used to treat prostate cancer.

How does it work?

  • It works by blocking the effects of male hormones such as testosterone.

When and how do I take it?

Always take Bicalutamide exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

  • The usual dose for an adult is one tablet each day.
  • Swallow the tablet whole with a drink of water.
  • Try to take your tablet at the same time each day.
  • Do not stop taking this medicine even if you feel well, unless your doctor tells you to.

What’s the dose?

The usual dose for an adult is one tablet each day.

Could it interact with other tablets?

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines that you buy without a prescription and herbal
medicines.

Do not take Casodex if you are already taking any of the following medicines:

  • Cisapride (used for some types of indigestion).
  • Certain anti-histamine medicines (terfenadine or astemizole).

Also, tell your doctor if you are taking any of the following medicines:

  • Medicines taken by mouth to prevent blood clots (oral anti-coagulants).
  • Ciclosporin (to suppress your immune system).
  • Calcium channel blockers (to treat high blood pressure or some heart conditions).

Herbal supplements should be used with caution and only after informing your doctor first.

What are the possible risks or side-effects?

Like all medicines, Bicalutamide can cause side effects, although not everybody gets them.

Allergic reactions:

These are uncommon (affect less than 1 in 100 people). The symptoms can include sudden onset of:

  • Rash, itching or hives on the skin.
  • Swelling of the face, lips, tongue, throat or other parts of the body.
  • Shortness of breath, wheezing or trouble breathing.

If this happens to you, see a doctor straight away. Also tell your doctor straight away if you notice any of the following:

Very common (affects more than 1 in 10 people):

  • Pain in your abdomen.
  • Blood in your urine.

Common (affects less than 1 in 10 people):

  • Yellowing of the skin or whites of your eyes (jaundice). These may be signs of liver problems or in rare cases (affects less than 1 in 1,000 people) liver failure.

Can I drink alcohol while taking it?

There are no known interactions between alcohol and Bicalutamide.
Always ask your doctor/pharmacist however as this may depend on what other tablets you are taking.

What if I’m pregnant/breastfeeding?

Bicalutamide cannot be taken by women.

 

If you have any more questions please ask your Pharmacist.

Remember to keep all medicines out of reach of children
Please Note:
 We have made every effort to ensure that the content of this information sheet is correct at time of publish, but remember that information about drugs may change. This sheet does not list all the uses and side-effects associated with this drug. For full details please see the drug information leaflet which comes with your medicine. Your doctor will assess your medical circumstances and draw your attention to any information or side-effects which may be relevant in your particular case.

References:

https://en.wikipedia.org/wiki/Bicalutamide

http://www.drugs.com/casodex.html

http://www.rxlist.com/casodex-drug.htm

http://chemocare.com/chemotherapy/drug-info/casodex.aspx

http://www1.astrazeneca-us.com/pi/casodex.pdf

http://www.macmillan.org.uk/Cancerinformation/Cancertreatment/Treatmenttypes/Hormonaltherapies/Individualhormonaltherapies/Bicalutamide.aspx

 

Health Reference: Prostate Cancer