Bisolvon helps you to breathe more easily when you have breathing problems such as bronchitis or sinusitis. It works by making your mucus thinner so that you can get rid of it more easily.

How to take Bisolvol

Always take this medicine exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

Taking this medicine

Take this medicine only by mouth. To make sure you use the right amount, use the measuring cup provided to measure your dose

If you prefer, you can use a 5 ml plastic spoon to use instead

  • Remove the measuring cup from the bottle cap before use
  • Fill the measuring cup up to the 5 ml line
  • Rinse the measuring cup with water after use

How much to take: Children between 2 and 5 years

  • The usual dose is 5 ml two times a day

Children between 5 and 12 years

  • The usual dose is 5 ml four times a day

Adults

  • The usual dose starts from 10 ml three times a day
  • However, you could be asked to take up to 15 ml four times a day.

Your doctor will tell you exactly how much you need to take

If you think this medicine is not working well enough

  • If your medicine does not seem to be working for you, talk to your doctor as soon as possible. Do not take extra Bisolvon unless your doctor tells you to.

If you take more Bisolvon than you should

  • If you take more of this medicine than you should, talk to a doctor or go to a hospital straight away. Take the medicine container with you even if there is no Bisolvon left.

If you forget to take Bisolvon

  • If you forget a dose, take it as soon as you remember it
  • However, if it is nearly time for the next dose, skip the missed dose
  • Do not take a double dose to make up for a forgotten dose

Side effects

Stop taking Bisolvon and see a doctor straight away if you notice any of the following serious side effects – you may need urgent medical treatment:

  • Serious allergic reactions that may cause swelling of face or throat, wheezing or sudden difficulties in breathing
  • Skin lesions such as severe blistering or peeling of your skin, mouth, throat, nose, eyes and genitals

If you notice any of these, stop taking Bisolvon and see a doctor straight away.

Other side effects

Uncommon

  • Feeling sick (nausea) or being sick (vomiting)
  • Pain in the upper part of your abdomen
  • Diarrhoea

Rare

  • Hypersensitivity reactions
  • Rash
  • Urticaria

The following side effects can also happen but the frequency of these is not known

Anaphylactic reactions including

  • anaphylactic shock, angioedema 
  • Severe cutaneous adverse reactions 
  • Tightness of your chest
  • Pruritus

In addition, an expected increase in the flow of mucus secretion will result from taking bisolvon.

Contraindications

  • Bisolvon Oral Solution is contraindicated in patients known to be hypersensitive to bromhexine or other components of the formulation.

Interactions

No clinically relevant unfavourable interactions with other medications, such as ampicillin, amoxicillin, oxytetracycline or erythromycin, have been reported.

Pregnancy and Breast feeding

Pregnancy

  • There are limited data from the use of bromhexine in pregnant women.
  • Pre-clinical studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. As a precautionary measure, it is preferable to avoid the use of Bisolvon during pregnancy.

Lactation

  • It is unknown whether bromhexine/metabolites are excreted in human milk.
  • A risk to the breastfed infant cannot be excluded.
  • Bisolvon should not be used during breast-feeding.

Effects on ability to drive and use machines

  • No studies on the effect on the ability to drive and use machines have been performed with Bisolvon.

Shelf life

  • Unopened: 3 years.
  • In-use: Use within 12 months of opening bottle.

Special precautions for storage

  • Store in the original container.

References:

https://www.hpra.ie/img/uploaded/swedocuments/2173773.PA0007_025_002.aa7cc0c2-c2ff-4b55-80c9-8e666ce5f551.000001Product%20Leaflet%20Approved.160429.pdf

https://www.medicines.ie/medicines/bisolvon-oral-solution-31446/

https://www.nps.org.au/medicine-finder/bisolvon-chesty-kids-oral-liquid

 

Health Reference: Cough