Does it work?
Several small human studies of atopic dermatitis suggest benefits of taking evening primrose oil by mouth. Large well-designed studies are needed before a strong recommendation can be made. Evening primrose oil is approved for atopic dermatitis in several countries.
Dangers and possible side effects...
Individuals who are allergic to plants in the Onagraceae family, gamma-linolenic acid or other ingredients in evening primrose oil should avoid the substance. Individuals with seizure disorders and pregnant or breastfeeding women should also avoid evening primrose oil.