Taxotere (Docetaxel) is used to treat locally advanced breast cancer (cancer that is widespread in the breast area) or secondary breast cancer (cancer that has spread to other parts of the body). It may also be used to treat primary breast cancer as part of a clinical trial.
Why have I been prescribed Taxotere?
- Taxotere (Docetaxel) is used to treat locally advanced breast cancer (cancer that is widespread in the breast area) or secondary breast cancer (cancer that has spread to other parts of the body).
- It may also be used to treat primary breast cancer as part of a clinical trial.
- Also used to treat non small cell lung cancer, prostate cancer, head and neck cancer and gastric adenocarcinoma.
How does it work?
- When normal cells start dividing structures called microtubules are formed.
- Once the cells stop dividing these microtubules are broken down or destroyed.
- However, with cancer cells Taxotere stops the microtubules from breaking down.
- The cells become blocked by microtubules so that they can’t grow and divide,
When and how do I take it?
Taxotere is given as a drip into a vein in the hand or arm and you will usually have four to six treatments as an outpatient. Taxotere is normally given every three weeks over a one-hour period. It may also be given weekly. Taxotere is sometimes given with other types of chemotherapy and anti-cancer drugs.
What’s the dose?
The dose is calculated according to body surface area so will be different for everyone.
Could they interact with other tablets?
- Taxotere may interact with other medicines which speed up or slow down the processing of drugs in the body therefore always tell you doctor or pharmacist that you are receiving Taxotere.
Herbal supplements should be used with caution and only after informing your doctor first.
What are the possible risks or side-effects?
- Hair loss (alopecia)
- Effects on the blood (low white or red cell count)
- Fluid retention and weight gain
- Numbness and/or tingling in hands or feet
- Nausea
- Diarrhoea
- Allergic reaction
- Painful muscles and joints
- Tiredness or fatigue
- Skin reactions
- Nail reactions
- Changes in heart rate
- Pain in the injection site
- Effects on the liver (temporary effects on how the liver works)
Can I drink alcohol while taking it?
- Taxotere may cause dizziness.
- This effect may be worse if you take it with alcohol.
What if I’m pregnant/breastfeeding?
- Taxotere must not be used during pregnancy unless clearly indicated.
Women of childbearing potential /contraception:
- Women of childbearing age receiving docetaxel should be advised to avoid becoming pregnant, and to inform the treating physician immediately should this occur.
- An effective method of contraception should be used during treatment.
- Breast feeding must be discontinued for the duration of docetaxel therapy.
If you have any more questions please ask your Pharmacist.
Remember to keep all medicines out of reach of children
Please Note: We have made every effort to ensure that the content of this information sheet is correct at time of publish, but remember that information about drugs may change. This sheet does not list all the uses and side-effects associated with this drug. For full details please see the drug information leaflet which comes with your medicine. Your doctor will assess your medical circumstances and draw your attention to any information or side-effects which may be relevant in your particular case.
References:
https://en.wikipedia.org/wiki/Docetaxel
http://chemocare.com/chemotherapy/drug-info/Taxotere.aspx
http://www.drugs.com/taxotere.html
http://www.breastcancer.org/treatment/druglist/taxotere
http://www.rxlist.com/taxotere-side-effects-drug-center.htm
http://www.cancerresearchuk.org/about-cancer/cancers-in-general/treatment/cancer-drugs/docetaxel
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