Konverge contains two substances called olmesartan medoxomil and amlodipine (as amlodipine besilate). Both of these substances help to control high blood pressure.

  • Olmesartan medoxomil belongs to a group of medicines called “angiotensin-II receptor antagonists” which lower blood pressure by relaxing the blood vessels.
  • Amlodipine belongs to a group of substances called “calcium channel blockers”. Amlodipine stops calcium from moving into the blood vessel wall which stops the blood vessels from tightening thereby also reducing blood pressure.
  • The actions of both these substances contribute to stopping the tightening of blood vessels, so that blood vessels relax and blood pressure decreases.
  • Konverge is used for the treatment of high blood pressure in patients whose blood pressure is not controlled enough with either olmesartan medoxomil or amlodipine alone.

Konverge with food and drink

  • Konverge can be taken with or without food. Swallow the tablet with some fluid (such as one glass of water). If possible, take your daily dose at the same time each day, for example at breakfast time.
  • Grapefruit juice and grapefruit should not be consumed by people who are taking Konverge.
This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active ingredient amlodipine, which can cause an unpredictable increase in the blood pressure lowering effect of Konverge.

Pregnancy and breastfeeding

Pregnancy

  • You must tell your doctor if you think that you are (or might become) pregnant.Your doctor will normally advise you to stop taking Konverge before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Konverge. Konverge is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
  • If you become pregnant during therapy with Konverge, please inform and see your physician without delay.

Breast-feeding

  • Tell your doctor if you are breast-feeding or about to start breast-feeding. Konverge is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast- feed, especially if your baby is newborn, or was born prematurely.
  • If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

How to take Konverge

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.

  • The recommended dose of Konverge is one tablet per day.
  • The tablets can be taken with or without food. Swallow the tablet with some fluid (such as a glass of water). The tablet should not be chewed. Do not take them with grapefruit juice.
  • If possible, take your daily dose at the same time each day, for example at breakfast time.

Side effects:

Common

  • dizziness
  • headache
  • swelling of ankles, feet, legs, hands, or arms
  • tiredness

Uncommon

  • dizziness on standing up
  • lack of energy
  • tingling or numbness of hands or feet
  • vertigo
  • strong heart beat
  • fast heart beat
  • low blood pressure with symptoms such as dizziness, light-headedness
  • laboured breathing
  • cough
  • nausea
  • vomiting
  • indigestion
  • diarrhoea
  • constipation
  • dry mouth
  • upper abdominal pain
  • skin rash
  • muscle spasms
  • pain in arms and legs
  • back pain
  • feeling more of an urge to pass urine
  • sexual inactivity
  • inability to get or maintain an erection
  • weakness

References

http://www.hpra.ie/img/uploaded/swedocuments/2124714.PA0865_017_001.39452df7-6765-48e4-a7ca-8c0f8eecb0c0.000001Product%20Leaflet%20Approved.131024.pdf

 

 

Health Reference: Hypertension