Hiccups are a common condition that affects nearly everyone. Hiccups involve the involuntary contraction of the diaphragm — the muscle that separates your chest from your abdomen and plays an important role in breathing.

What is it?

  • Hiccups are a common condition that affects nearly everyone. Hiccups involve the involuntary contraction of the diaphragm — the muscle that separates your chest from your abdomen and plays an important role in breathing. Each contraction is followed by a sudden closure of your vocal cords, which produces the characteristic "hic" sound.
  • Many people have home remedies for hiccups that they swear by, ranging from breathing into a paper bag to swallowing a teaspoon of granulated sugar.
  • Hiccups may result from a large meal, alcoholic beverages or sudden excitement. Rarely, hiccups may be a sign of an underlying medical condition. A bout of hiccups usually lasts only a few minutes. But in some people, about one in 100,000, hiccups may persist for months.
This can result in malnutrition and exhaustion.

Symptoms

The characteristic sound of a hiccup, sometimes preceded by a slight tightening sensation in your chest, abdomen or throat, are the only signs and symptoms associated with hiccups. The number of hiccups a minute typically ranges between four and 60.

Causes

The most common triggers for short-term hiccups include:

  • Eating too much
  • Drinking carbonated beverages
  • Excessive consumption of alcohol
  • Sudden temperature changes
  • Excitement or emotional stress

Hiccups that last more than 48 hours may be caused by a variety of factors, which are generally grouped into the following categories:

Nerve damage or irritation

The most common cause of long-term hiccups is damage or irritation of the vagus nerves or phrenic nerves, which serve the diaphragm muscle. Factors that may cause damage or irritation to these nerves include:

  • A hair or something else in your ear touching your eardrum
  • Sore throat or laryngitis
  • A tumor, cyst or goiter in your neck
  • Gastroesophageal reflux

Central nervous system disorders

A tumor or infection in your central nervous system or damage to your central nervous system as a result of trauma can disrupt your body's normal control of the hiccup reflex. Examples include:

Metabolic disorders and drugs

Risk factors

Sex

Men are much more likely to develop long-term hiccups than are women.

Surgery

Several factors related to surgical procedures appear to increase your risk of developing long-term hiccups. They include:

  • General anesthesia
  • Intubation, in which a tube is placed down your throat to help you breathe
  • Neck extension, which is necessary during intubation
  • Abdominal distension, which is common after endoscopic procedures performed through small incisions
  • Organ manipulation

Mental or emotional issues

Anxiety, stress and excitement have been associated with some cases of short-term and long-term hiccups. 

Complications

Prolonged hiccups may interfere with:

  • Speech
  • Eating
  • Sleeping
  • Post-surgical wound healing

Diagnosis

If your doctor suspects an underlying medical condition may be causing your hiccups, he or she may recommend one or more of the following tests:

Laboratory tests

Samples of your blood may be checked for signs of:

Imaging tests

These types of tests may be able to detect anatomical abnormalities that may be affecting the vagus nerve, phrenic nerve or diaphragm. Imaging tests may include:

  • Chest X-ray
  • Computerized tomography (CT) scan
  • Magnetic resonance imaging (MRI)

Endoscopic tests

These procedures utilize a thin, flexible tube containing a tiny camera, which is passed down your throat to check for problems in your esophagus or windpipe. 

References:

http://www.nhs.uk/Conditions/Hiccup/Pages/Treatment.aspx

http://www.medicinenet.com/hiccups/article.htm

http://www.emedicinehealth.com/hiccups/article_em.htm

https://en.wikipedia.org/wiki/Hiccup