We go through the different types of insulin available to treat diabetes.
Types of Insulin
Endogenous insulin refers to the insulin made inside the body by the pancreas. Exogenous insulin refers to the insulin made or retrieved from outside of the body. Exogenous insulin is the type of insulin injected or infused via an insulin pump. Many different types of insulin are available through the pharmacy—a prescription and specific instructions from a health-care provider are required.
Exogenous insulins differ by:
How they are made or where they are retrieved from
The duration of action—how long they work
Their onset of action—how quickly it starts working
When the action peaks—when they are most effective
Usually reaches the bloodstream within 30 minutes after injection
Peaks anywhere from 2 to 3 hours after injection
Is effective for approximately 3 to 6 hours
Types: Humulin R,
Intermediate-Acting Insulin
Generally reaches the bloodstream about 2 to 4 hours after injection
Peaks 4 to 12 hours later
Is effective for about 12 to 18 hours
Types: NPH (Humulin N,
Long-Acting Insulin
Reaches the bloodstream several hours after injection
Tends to lower glucose levels fairly evenly over a 24-hour period
Types: Insulin detemir (Levemir) and insulin glargine (Lantus)
Premixed insulin
Premixed insulin benefits people who have difficulty drawing up insulin out of two bottles and drawing up accurate doses. Premixed insulin is also convenient for people whose diabetes has been maintained on this combination.