Molipaxin (Trazodone) Capsules can be used to treat anxiety and depression

Why have I been prescribed Molipaxin?

Molipaxin (Trazodone) Capsules can be used to treat anxiety and depression.

How does it work?

Molipaxin works by correcting the imbalance of two chemicals (noradrenaline and serotonin) which are known to be decreased in depression.

When and how do I take it?

Take this medicine by mouth:

  • Swallow the capsules whole with a drink of water
  • Take with or after food. This can help lower the chances of side effects
  • If you have been told to take Molipaxin Capsules only once each day then you should take it before going to bed

What’s the dose?



  • Adults usually start by taking 150mg each day
  • Your doctor may increase the dose to 300mg each day depending on your condition
  • For adults in hospital the dose may be as high as 600mg each day


  • Adults usually start by taking 75mg each day
  • Your doctor may increase the dose to 300mg each day


  • Older people or those who are frail will usually be given a starting dose of 100mg each day.

Could it interact with other tablets?

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines you buy without a prescription. This is because Molipaxin Capsules can affect the way some other medicines work. Also some medicines can affect the way Molipaxin Capsules work.

Tell your doctor if you are taking any of the following medicines:

  • MAOI (MonoAmine Oxidase Inhibitors) medicine such as tranylcypromine, phenelzine and isocarboxazid (for depression) or selegiline (for Parkinson’s disease), or have taken them in the last 2 weeks
  • Other antidepressants
  • Sedatives (such as tranquilizers or sleeping pills)
  • Medicines used to treat epilepsy such as carbamazepine and phenytoin
  • Medicines used to treat high blood pressure, for example, clonidine
  • Digoxin (used to treat heart problems)
  • Medicines used to treat fungal infections such as ketoconozole and itraconazole
  • Some medicines used to treat HIV such as ritonavir and indinavir
  • Eyrthromycin, an antibiotic used to treat infections

Herbal products should also only be taken after talking with your doctor.

What are the possible risks or side-effects?

Like all medicines, Molipaxin Capsules can cause side effects, although not everybody gets them.

Stop taking Molipaxin Capsules and see a doctor or go to a hospital straight away if:

  • You get swelling of the hands, feet, ankles, face, lips or throat which may cause difficulty swallowing or breathing, itching of the skin and nettle rash.

This may mean you are having an allergic reaction to Molipaxin Capsules.

  • Painful erection of the penis, unrelated to sexual activity, that will not go away (priapism)
  • Yellowing of the eyes or skin. This could be a liver problem (such as jaundice)
  • Getting infections more easily than usual. This could be because of a blood disorder (agranulocytosis)
  • Bruising more easily than usual. This could be because of a blood disorder (thrombocytopenia)

Talk to your doctor straight away if you notice the following side-effects:

  • Feeling tired, faint, dizzy, having pale skin. These could be signs of anaemia
  • Convulsions/fits
  • Unusual skin sensations such as numbness, tingling, pricking, burning or creeping on the skin (paraesthesia)
  • Feeling confused, restless, sweating, shaking, shivering, hallucinations (strange visions or sounds), sudden jerks of the muscles or a fast heartbeat, you may have something called Serotonin syndrome
  • Feeling very unwell possibly with shortness of breath (dyspnoea), difficulty in walking or walking with a shuffling gait, shaking, uncontrolled muscle twitching, and a high temperature (above 38ºC).

Can I drink alcohol while taking it?

  • You should avoid drinking alcohol while taking Molipaxin Capsules.

What if I’m pregnant/breastfeeding?

Molipaxin should not be used in pregnancy unless your doctor deems it necessary. It is not recommended foe use while breast feeding.

If you have any more questions please ask your Pharmacist.

Remember to keep all medicines out of reach of children
Please Note:
We have made every effort to ensure that the content of this information sheet is correct at time of publish, but remember that information about drugs may change. This sheet does not list all the uses and side-effects associated with this drug. For full details please see the drug information leaflet which comes with your medicine. Your doctor will assess your medical circumstances and draw your attention to any information or side-effects which may be relevant in your particular case.



Health Reference: Anxiety, Depression