Optimax (L-Tryptophan) is used in the treatment of depression when other treatments have not worked, and as an add-on treatment to other anti-depressant medication.

Why have I been prescribed Optimax?

OPtimax (L-Tryptophan) is used in the treatment of depression when other treatments have not worked, and as an add-on treatment to other anti-depressant medication.

How does it work?

Optimax restores the levels of a chemical called serotonin in the brain which is known to be decreased in depression.

When and how do I take it?

The tablets are usually taken three times a day with a glass of water and preferably after food.

What’s the dose?


  • The usual dose is two tablets, three times daily; for some patients, up to 6g L-tryptophan may be required.

Could it interact with other tablets?

Tell your doctor or pharmacist if you are taking, or have recently taken any other medication, including non-prescription items. Especially tell your doctor or pharmacist if you are taking any of the following:

  • Other anti-depression medication called MAOI’s or SSRI’s.
  • Phenothiazines (anti-psychotic or some antihistaminic medication)or benzodiazepines (for anxiety)

Herbal products should also only be taken after talking with your doctor.

What are the possible risks or side-effects?

  • In some patients, Optimax may cause a slight feeling of nausea which usually disappears within 2 or 3 days.
  • Such nausea can be minimised by taking it after food.
  • Other adverse reactions include headache and light-headedness.
  • Cases of suicidal thoughts and suicidal behaviours have been reported while taking Optimax or early after treatment discontinuation.

Can I drink alcohol while taking it?

There are no known interactions between alcohol and Tryptophan.

Always ask you doctor or pharmacist however as other medications you are taking may have a bearing on this.

What if I’m pregnant/breastfeeding?

You should tell your doctor if are, or plan on becoming pregnant or breast feeding as he will have to decide if it’s safe for you to take Optimax.

If you have any more questions please ask your Pharmacist.

Remember to keep all medicines out of reach of children
Please Note:
We have made every effort to ensure that the content of this information sheet is correct at time of publish, but remember that information about drugs may change. This sheet does not list all the uses and side-effects associated with this drug. For full details please see the drug information leaflet which comes with your medicine. Your doctor will assess your medical circumstances and draw your attention to any information or side-effects which may be relevant in your particular case.







Health Reference: Depression